| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10541138 | Food Chemistry | 2012 | 6 Pages |
Abstract
⺠Chronic ethanol feeding induced microsomal CYP2E1 but lowered HO-1 of rat liver. ⺠Excessive ethanol caused microsomal oxidative stress and liver dysfunction. ⺠Ethanol-derived detrimental effects were alleviated by quercetin pretreatment. ⺠Quercetin induced HO-1, which was not completely abolished by ethanol. ⺠HO-1 induction by quercetin may antagonize CYP2E1-mediated microsomal stress.
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Authors
Yuhan Tang, Chao Gao, Yanru Shi, Liping Zhu, Xiaomin Hu, Di Wang, Yang Lv, Xuefeng Yang, Liegang Liu, Ping Yao,