| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10541219 | Food Chemistry | 2012 | 8 Pages |
Abstract
⺠Eukaryotic DNA polymerase (pol) inhibitors from soybean were screened. ⺠Two novel glucosyl compounds (a cerebroside and a steroidal glycoside) were isolated. ⺠They selectively inhibited in vitro pol λ activity for nine mammalian pols. ⺠They suppressed in vivo inflammation in a similar manner as pol λ inhibition. ⺠These compounds from soybean may be useful for their anti-inflammatory properties.
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Authors
Yoshiyuki Mizushina, Yoshihiro Takahashi, Yoshihiro Sato, Yasuhiro Yamaguchi, Toshifumi Takeuchi, Isoko Kuriyama, Fumio Sugawara, Hiromi Yoshida,