Combining the observation of cell morphology with the evaluation of key inflammatory mediators to assess the anti-inflammatory effects of geranyl flavonoid derivatives in breadfruit

Article ID	Journal	Published Year	Pages	File Type
10541248	Food Chemistry	2012	8 Pages	PDF

Abstract

âº Geranyl flavonoid derivatives including a new compound are isolated from the fruit of Artocarpus communis (breadfruit). âº Assessing the anti-inflammatory effects of geranyl flavonoid derivatives by a novel approach. âº Geranyl flavonoid derivatives have potent implications to prevent diabetic inflammation.

Keywords

COX-2 Artocarpus communis RAGE S100B THP-1 DCF-DA IL-6 NF-κB ROS inflammation interleukin-6 tumour necrosis factor-α Cyclooxygenase-2 TNF-α nuclear factor-κB S100B protein Reactive oxygen species