Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10541509 | Food Chemistry | 2011 | 6 Pages |
Abstract
⺠Hydroxyprolyl-glycine (Hyp-Gly) was identified in human blood after collagen hydrolysate ingestion. ⺠Phenyl isothiocyanate derivatisation of peptides improved resolution of food-derived collagen peptides by RP-HPLC. ⺠The ratio of Hyp-Gly to Pro-Hyp depended on subjects who ingested elastin hydrolysate. ⺠Hyp-Gly was less susceptible to human serum peptidase than Pro-Hyp. ⺠Hyp-Gly extensively enhanced the growth of mouse primary fibroblasts on collagen gel in a higher extent than Pro-Hyp.
Related Topics
Physical Sciences and Engineering
Chemistry
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Authors
Yasutaka Shigemura, Saeko Akaba, Eriko Kawashima, Eun Young Park, Yasushi Nakamura, Kenji Sato,