Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10541606 | Food Chemistry | 2012 | 7 Pages |
Abstract
⺠We isolated a new cerebroside and nine glycolipids from the aerial parts of Orostachys japonicus. ⺠Some of the glycolipids inhibited fatty acid synthase (FAS) with micromolar IC50 values. ⺠The glycolipids with FAS inhibitory activity showed cytotoxic activity against HL-60 and A549 cancer cells. ⺠Our findings may provide a scientific basis for a folk remedy, using the plant to treat cancer.
Related Topics
Physical Sciences and Engineering
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Authors
HaiYan Zhang, Joonseok Oh, Tae-Su Jang, Byung Sun Min, MinKyun Na,