| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10541628 | Food Chemistry | 2012 | 6 Pages |
Abstract
⺠Dietary xenobiotics may interfere with drug metabolism in humans. ⺠Food-drug interactions include the induction of cytochromes P450 via xenoreceptors. ⺠We examined activation of PXR/AhR, and induction of P450 by ready to drink teas. ⺠Human hepatocytes and cell lines HepG2 and LS174T were used as in vitro models. ⺠Three teas induced CYP3A4 and several teas elevated CYP1A1 or activated AhR.
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Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Alzbeta Kamenickova, Radim Vrzal, Zdenek Dvorak,