Sweeteners interacting with the transmembrane domain of the human sweet-taste receptor induce sweet-taste synergisms in binary mixtures

Article ID	Journal	Published Year	Pages	File Type
10542033	Food Chemistry	2012	8 Pages	PDF

Abstract

âº The sweet intensity was measured by using the cells expressing sweet-taste receptor. âº NHDC and cyclamate enhanced the response of the sweet-taste receptor. âº We identified a residue for NHDC in eliciting a synergistic potentiation. âº Our study may provide additional insight into receptor-based synergisms of sweetness.

Keywords

GPCR TMD Cyclamate Neohesperidin dihydrochalcone Venus Flytrap module Calcium imaging transmembrane domain wild-type Taste receptor G protein-coupled receptor

Related Topics

Physical Sciences and Engineering Chemistry Analytical Chemistry

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Sweeteners interacting with the transmembrane domain of the human sweet-taste receptor induce sweet-taste synergisms in binary mixtures

Authors

Satoshi Fujiwara, Takamasa Imada, Tomoya Nakagita, Shinji Okada, Takashi Nammoku, Keiko Abe, Takumi Misaka,