Article ID Journal Published Year Pages File Type
10542335 Food Chemistry 2013 7 Pages PDF
Abstract
In the antimutagenicity assays, these luteolin derivatives showed antimutagenic effects in deletion and intrachromosomal recombination events against ethyl methanesulfonate and acridine mutagen agents. In deletion events, the highest inhibition rates for luteolin-7-O-glucoside, luteolin-7-O-rutinoside and luteolin-7-O-glucuronide against ethyl methanesulfonate were 57.6%, 58.3% and 62.5%, respectively. Likewise, the highest inhibition rates for luteolin-7-O-glucoside, luteolin-7-O-rutinoside and luteolin-7-O-glucuronide against acridin were 21.8%, 22.4% and 23.6%, respectively. Our findings showed that these luteolin derivatives have stronger antimutagenic properties against ethyl methanesulfonate compared to the acridine mutagen agent.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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