Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10542375 | Food Chemistry | 2013 | 7 Pages |
Abstract
Tamarillo (Solanum betaceum) is a tropical exotic fruit whose polysaccharides were extracted from the ripe pulp. After various purification steps, homogeneous fractions (designated PTW, STK-1000R and PF) were analyzed by sugar composition, HPSEC, methylation and NMR spectroscopy analysis. The results showed that the fraction PTW consisted of a linear arabinan with (1 â 5)-linked α-l-arabinofuranosyl units. Fractions designated as STK-1000R and PF contained galactoarabinoglucuronoxylans, with (1 â 4)-linked β-d-Xylp residues in the backbone, carrying branches exclusively at O-2. The polysaccharide in STK-1000R is less branched than that in the PF fraction (â¼20.0% and 36.5%, respectively), with side-chains formed by (1 â 5)-linked α-l-Araf residues and (1 â 4)-linked α-d-GlcpA residues and with non-reducing end units formed by α-l-Araf, β-Arap, β-d-Galp, α-d-GlcpA and 4-O-Me-α-d-GlcpA. Intraperitoneal administration of the STK-1000R fraction in mice significantly reduced the number of abdominal constrictions induced by 0.6% acetic acid and the inflammatory phase of nociception induced by 2.5% formalin, indicating that that fraction has an antinociceptive effect on inflammatory pain models.
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Authors
Georgia Erdmann do Nascimento, Leticia Alencar Hamm, Cristiane H. Baggio, Maria Fernanda de Paula Werner, Marcello Iacomini, Lucimara M.C. Cordeiro,