Article ID Journal Published Year Pages File Type
10543046 Food Chemistry 2011 8 Pages PDF
Abstract
► This is first report elucidating the mechanism of mangostins against Wnt signalling. ► Mangostins decrease β-catenin via repressing its transcription not its degradation. ► The regulation of β-catenin is due to regulation of cGMP and PKG by mangostins.
Keywords
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
Preview
α- and γ-Mangostin inhibit the proliferation of colon cancer cells via β-catenin gene regulation in Wnt/cGMP signalling
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