Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10548227 | Journal of Chromatography A | 2005 | 5 Pages |
Abstract
A non-destructive, fast and environmentally friendly procedure has been developed for cocaine determination in euro bank notes. Cocaine was extracted with 15 ml methanol by vortex agitation during 5 min. The extract was evaporated and reconstituted in 0.5 ml methanol. GC-MS-MS analysis was performed using as precursor ion m/z 182.2, with an excitation energy voltage of 1.60 eV, being the product ions measured m/z 150.2 and 82.0. A limit of detection of 0.15 ng per note and a repeatability of 6%, established from the relative standard deviation, of a 1 ng mlâ1 level, were achieved. Recoveries of 101 ± 2 and 98 ± 3% were obtained for samples spiked with 100 and 10 μg respectively. Results show that all the euro bank notes measured (16 samples) were contaminated with cocaine in the range between 1.25 and 889 μg. Two different contamination levels, high level (150-889 μg) and low one (1.25-77 μg) were found and it could be related with the direct or indirect contact with the drug.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Francesc A. Esteve-Turrillas, Sergio Armenta, Javier Moros, Salvador Garrigues, AgustÃn Pastor, Miguel de la Guardia,