Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10550170 | Journal of Chromatography B | 2005 | 4 Pages |
Abstract
This communication describes the invention and further development of the first 96-well solid-phase extraction system and the original purposes to which it was put. We also describe the adaption of this system for bioanalysis of pharmaceutically active small molecules and the needs underlying it. The system has become a world-wide standard for high-throughput bioanalysis and has been extended by others to include, for example, disk-phase extraction and supported liquid-liquid extraction, as well as 384-well systems. The factors that enabled this leap forward in productivity are discussed.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Richard F. Venn, James Merson, Susan Cole, Paul Macrae,