| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10550955 | Journal of Chromatography B | 2011 | 6 Pages |
Abstract
There is considerable evidence that stilbenes provide health benefits. Trans-piceid is one of the major stilbenoid compounds in red wine and other plants. The purpose of this study is to investigate the metabolism of piceid in rats, including its conversion product by intestinal microflora in vitro and urinary metabolites. A HPLC-MS/MS method with electrospray ionization (ESI), negative ion mode and collision induced dissociation (CID), was used to elucidate the structures of the major metabolites of piceid. Three metabolites resveratrol, dihydropiceid and dihydroresveratrol were detected after incubating with gut microbiota for 5Â h. Four urinary metabolites of piceid were identified as resveratrol, dihydroresveratrol monosulfate, piceid monosulfate and piceid monoglucuronide.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Donggeng Wang, Zhiwen Zhang, Jianfeng Ju, Xinyang Wang, Wenjing Qiu,