Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10553594 | Journal of Pharmaceutical and Biomedical Analysis | 2011 | 4 Pages |
Abstract
Boron phenylalanine is one of the lead drug candidates in the field of Boron Neutron Capture Therapy. Its inherent low toxicity allows large doses to be administered, but this makes it important to identify, rationalise and quantify impurities. Here we report a chromatographic assay method, the conditions under which the parent compound is unstable, and the suggested degradation mechanisms.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Lindsay Dick, Neil Dooley, Moira A. Elliott, Steven J. Ford, Malcolm R. Gordon, Gavin W. Halbert, William J. Kerr,