Article ID Journal Published Year Pages File Type
10553620 Journal of Pharmaceutical and Biomedical Analysis 2009 5 Pages PDF
Abstract
The ELISA method, used in determination of the main nicotine metabolites showed high accuracy and sensitivity. However, this method was less specific than the reference technique (TLC). The high correlation coefficients, r > 0.9, between the results of determined nicotine metabolites in urine by means of ELISA and TLC with densitometry confirmed the possibility of the application of ELISA method to practical monitoring of tobacco smoke exposure in large population groups.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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