Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10553993 | Journal of Pharmaceutical and Biomedical Analysis | 2005 | 7 Pages |
Abstract
Experimentally measured IAM chromatography retention values and calculated molecular descriptors and solubility parameters can be used to predict intestinal absorption of drugs in humans. Developed QSAR can be used as a screening method in the designing of drugs with appropriate IA and for the selection of drug candidates in the early stage of drug discovery process.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
T.E. Yen, S. Agatonovic-Kustrin, A.M. Evans, R.L. Nation, J. Ryand,