Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10554000 | Journal of Pharmaceutical and Biomedical Analysis | 2005 | 4 Pages |
Abstract
In this paper, a simple, rapid and sensitive spectrofluorimetric method based on the formation of yttrium complexes has been developed for the determination of norfloxacin (NFLX). The affecting factors of the enhancement were studied in detail. Under optimum conditions, a linear relationship was obtained between the enhanced fluorescence intensity and the NFLX concentration in the range 1.0 Ã 10â9 to 1.0 Ã 10â5 mol/l and the detection limit of NFLX was 3.8 Ã 10â11 mol/l (S/N = 3). The method is applied for the determination of NFLX in actual sample (norfloxcain eye drops), the average recovery is 102.4% (n = 5), and the result obtained is satisfactory.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Yunxiao Han, Xia Wu, Jinghe Yang, Shuna Sun,