Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10556045 | Journal of Proteomics | 2012 | 11 Pages |
Abstract
⺠Balofloxacin-resistant V. alginolyticus was analyzed by native/SDS-PAGE proteomics. ⺠Alteration of NqrA and NqrF from Na(+)-NQR was detected. ⺠Western blotting confirmed downregulation of NqrA, NqrF. ⺠Overexpression of NqrA and NqrF validated the role of the two proteins. ⺠Downregulation of NQR complex is crucial for balofloxacin resistance in this bacterium.
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Authors
Peipei Li, Xianjie Liu, Hui Li, Xuan-Xian Peng,