Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10556063 | Journal of Proteomics | 2012 | 13 Pages |
Abstract
⺠2D-DIGE was used for the first time to study obesity based on omental fat. ⺠Twenty proteins were up-regulated and 24 down-regulated in response to obesity. ⺠Diminished metabolism is a hallmark of obesity. ⺠The up-regulated proteins evidence morphological changes in the obese adipocytes. ⺠TKT and ACY-1 are newly described proteins with an important role in obesity.
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Authors
Rafael Pérez-Pérez, Eva GarcÃa-Santos, Francisco J. Ortega-Delgado, Juan A. López, Emilio Camafeita, Wifredo Ricart, José-Manuel Fernández-Real, Belén Peral,