Article ID Journal Published Year Pages File Type
10556067 Journal of Proteomics 2012 13 Pages PDF
Abstract
► We identify the proteins involved in 5-fluorouracil resistance. ► Up-regulation of 7 anti-apoptotic proteins. ► Down-regulation of 4 proapoptotic proteins. ► Phosphorylated HSPB1 may play an important role in 5-FU resistance. ► We identify phosphorylated residues as Ser-15 and Ser-82 using 2-DE and MALDI-TOF/TOF.
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Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
Preview
Identification of phosphorylated serine-15 and -82 residues of HSPB1 in 5-fluorouracil-resistant colorectal cancer cells by proteomics
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