| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10556093 | Journal of Proteomics | 2012 | 7 Pages |
Abstract
⺠We performed the first exploratory LC-MS study of human urine in the context of febrile, complicated urinary tract infection. ⺠Multivariate data analysis revealed O-glycopeptides as the main UTI specific features. ⺠The identification of those features as O-glycosilated fibrinogen alpha chain fragments required a multi-MS platform approach. ⺠We suggest that these O-glycosilated fibrinogen alpha chain fragments could be possible markers of febrile UTI.
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Authors
Tiziana Pacchiarotta, Paul J. Hensbergen, Manfred Wuhrer, Cees van Nieuwkoop, Ekaterina Nevedomskaya, Rico J.E. Derks, Bart Schoenmaker, Carolien A.M. Koeleman, Jaap van Dissel, André M. Deelder, Oleg A. Mayboroda,