| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10556234 | Journal of Proteomics | 2011 | 12 Pages |
Abstract
⺠High-throughput proteomics identified major cartilage secretome proteins. ⺠Western blotting confirmed the presence of CILP-1, CLU, MMP-1, MMP-3 and TSP-1. ⺠Treatment with IL-1β increased MMP-1, MMP-3 and TSP-1. ⺠The proteins identified are involved in cartilage function and early stress responses. ⺠This approach may be used to study changes in the early stages of osteoarthritis.
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Analytical Chemistry
Authors
Abigail L. Clutterbuck, Julia R. Smith, David Allaway, Pat Harris, Susan Liddell, Ali Mobasheri,