Unadapted and adapted to starvation Acholeplasma laidlawii cells induce different responses of Oryza sativa, as determined by proteome analysis

► We studied the phytopathogenicity toward O. sativa L. of unadapted and adapted to unfavorable environment A. laidlawii cells. ► The qualitative and quantitative responses of the plant proteome toward adapted and unadapted mycoplasma cells differed. ► 82 proteins that were differentially expressed in adapted and unadapted mycoplasma cells were detected. ► In adapted cells of the mycoplasma, in comparison with unadapted ones, a significant increase in the expression of PNPase. ► There was also decreased expression of 40 proteins including 14 involved in bacterial virulence.