Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10556312 | Journal of Proteomics | 2012 | 14 Pages |
Abstract
⺠An in vivo model and DIGE were used to analyze changes in swine mesenteric lymph nodes upon S. typhimurium infection. ⺠Proteome response was associated to phagocyte infiltration, cytoskeleton remodeling and pyroptosis. ⺠Cross-presentation of S. typhimurium antigens via MHC-I in a proteasome-dependent manner was suggested. ⺠Reduction of S. typhimurium in tissue was associated to the induction of host innate and adaptive responses.
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Authors
Rodrigo Prado Martins, Melania Collado-Romero, Montserrat MartÃnez-Gomáriz, Ana Carvajal, Concepción Gil, Concepción Lucena, Ángela Moreno, Juan J. Garrido,