| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10556316 | Journal of Proteomics | 2012 | 15 Pages |
Abstract
⺠Proteins of Salmonella enterica serovar Typhimurium associated with triclosan defence and tolerance were identified. ⺠Exposure to triclosan induced a general stress response. ⺠In a triclosan tolerant mutant, the triclosan target, FabI, was up-regulated and mutated. ⺠Tolerance to triclosan involved modifications in metabolism, transport and permeability. ⺠Triclosan tolerance was associated with de-repressed efflux systems.
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Authors
O. Condell, Á. Sheridan, K.A. Power, R. Bonilla-Santiago, K. Sergeant, J. Renaut, C. Burgess, S. Fanning, J.E. Nally,