| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10556334 | Journal of Proteomics | 2011 | 16 Pages |
Abstract
⺠Modular chemical probes enable the isolation of subproteomes defined by functional small molecule-protein interactions. ⺠Leading strategies are Activity-based protein profiling, affinity pulldown, and Capture Compound mass spectrometry. ⺠Profiling small molecule-protein interactions contributes to the functional annotation of genomes. ⺠The approaches enable unbiased direct proteomic screens to identify all proteins that interact with a given drug molecule.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Thomas Lenz, Jenny J. Fischer, Mathias Dreger,