IPM: An integrated protein model for false discovery rate estimation and identification in high-throughput proteomics

Article ID	Journal	Published Year	Pages	File Type
10556335	Journal of Proteomics	2011	6 Pages	PDF

Abstract

âº We integrate two successful approaches to protein identification and FDR estimation. âº The methods showed great consistency in the list of identified proteins. âº Integrating the methods increases the number low abundance protein identifications.

Keywords

FDR IPM PSM LIPs Spire Identification Protein identification Mass spectrometry true positive false positive false discovery rate

Related Topics

Physical Sciences and Engineering Chemistry Analytical Chemistry

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IPM: An integrated protein model for false discovery rate estimation and identification in high-throughput proteomics

Authors

Roger Higdon, Lukas Reiter, Gregory Hather, Winston Haynes, Natali Kolker, Elizabeth Stewart, Andrew T. Bauman, Paola Picotti, Alexander Schmidt, Gerald van Belle, Ruedi Aebersold, Eugene Kolker,