Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10556339 | Journal of Proteomics | 2011 | 9 Pages |
Abstract
⺠Dasatinib and imatinib Capture Compounds were synthesized ⺠Drug-protein interactions were profiled in comparison to staurosporine ⺠Distinct kinase inhibitor specific sub-kinomes were identified ⺠Specific capturing of the kinase p38α was observed with the imatinib Capture Compound ⺠Specific non-kinase off-targets were identified for both imatinib and dasatinib
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Authors
Jenny J. Fischer, Christian Dalhoff, Anna K. Schrey, Olivia Y. Graebner neé Baessler, Simon Michaelis, Kathrin Andrich, Mirko Glinski, Friedrich Kroll, Michael Sefkow, Mathias Dreger, Hubert Koester,