Article ID Journal Published Year Pages File Type
10556401 Journal of Proteomics 2012 10 Pages PDF
Abstract
► We assessed the ability of whole-cell MALDI-TOF MS to identify activation states of macrophages. ► Macrophage polarisation patterns M1 and M2 were clearly identified by specific fingerprints. ► Whole-cell MALDI-TOF MS allowed the identification of subtypes of M1 and M2 polarisation patterns. ► Macrophages stimulated with various bacteria exhibited specific fingerprints. ► These specific fingerprints may help to study immune cells activation in pathological conditions.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
Authors
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