| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10556423 | Journal of Proteomics | 2012 | 10 Pages |
Abstract
⺠Low prohibitin 1 increases sensitivity to methionine and choline deficient diet. ⺠Low prohibitin 1 impairs lipid metabolism in hepatocytes by inactivation of AMPK. ⺠Prohibitin 1 deficient mice display increased production of proâinflammatory cytokines. ⺠Depletion of prohibitin 1 increases sensitivity to proâinflammatory aggressions. ⺠Low prohibitin 1 sensitizes splenocytes by deregulation of SHP1 and GSK3β.
Keywords
VCAMvascular cell adhesion proteinHMOXTNFProhibitin 1Methionine and choline deficient dietLIXShp1PF-4AMP kinaseMCDDLCKAMPKTPOGSKLPSETFTLRMIPIPAPHBADHPP2ADUSPLiver injuryaldehyde dehydrogenaseinflammationinterleukinIngenuity Pathway Analysistoll like receptordual specificity phosphatasePlatelet factor 4tumor necrosis factorBacterial lipopolysaccharideProhibitinProteomicsmacrophage inflammatory proteinglycogen synthase kinase
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Virginia Sánchez-Quiles, VÃctor Segura, Emilie Bigaud, Bin He, Bert W. O'Malley, Enrique SantamarÃa, Jesús Prieto, Fernando J. Corrales,