| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10556449 | Journal of Proteomics | 2012 | 11 Pages |
Abstract
⺠Nine different extraction tools tested on 400,000 CID and HCD tandem MS spectra data generated on an Orbitrap Velos. ⺠Extraction tools differ with regard to assigned charge states of precursors and fragment ion filtering. ⺠Higher resolution tandem MS data can benefit from charge state deconvolution of fragment ions. ⺠Charge state deconvolution of fragment ions is favorable for > 2+ peptides. ⺠Approx. 20% overlap of matches (p > .0.05) when comparing peak lists generated by 9 different tools.
Related Topics
Physical Sciences and Engineering
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Authors
Francesco Mancuso, Jakob Bunkenborg, Michael Wierer, Henrik Molina,