| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10556483 | Journal of Proteomics | 2012 | 12 Pages |
Abstract
⺠Doxorubicin-induced changes in cardiac phosphoproteome were analysed using the perfused heart model. ⺠2-DE, phosphospecific staining and mass spectrometry were combined. ⺠22 proteins with a significantly changed phosphorylation status were identified. ⺠Selected results were validated by immunoblotting. ⺠The results are relevant for doxorubicin-induced energy imbalance and myofibrillar disorganization.
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Authors
Séverine Gratia, Laurence Kay, Sylvie Michelland, Michel Sève, Uwe Schlattner, Malgorzata Tokarska-Schlattner,