| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10556488 | Journal of Proteomics | 2012 | 17 Pages |
Abstract
⺠148 glycation sites and 54 glycated proteins were identified in native human CSF. ⺠149 glycation sites were additionally detected by in vitro glycated CSF. ⺠In vitro glycation showed increases up to ten folds for some glycated proteins. ⺠Neuroinflammation and neurological disease were related with glycated CSF proteins.
Keywords
pgdsHCDCMLAGEsIPAβ2MCJDFDRIAARAGEsCIDPTMBACNε-(carboxymethyl)lysineCollision-induced dissociationNeurodegenerative disordersamyotrophic lateral sclerosispost-translational modificationhigher-energy collisional dissociationTEABAlzheimer's diseaseALSParkinson's diseaseIngenuity Pathway AnalysisCNSVascular dementiaTCEPSODSuperoxide dismutasecentral nervous systemFructoselysineCerebrospinal fluidCSFMethylglyoxalAdvanced glycation end productsMgOBeta-2 microglobulinGene ontologyProstaglandin D2 synthaseBoronate affinity chromatographyNonenzymatic glycationiodoacetamide
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
MarÃa RamÃrez-Boo, Feliciano Priego-Capote, Alexandre Hainard, Florent Gluck, Pierre Burkhard, Jean-Charles Sanchez,