| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10556490 | Journal of Proteomics | 2012 | 10 Pages |
Abstract
⺠PGL-1 is an RNA-binding protein component of germ granules in nematode C. elegans. ⺠We performed a comparative proteomic analysis between wild type and pgl-1 mutants using 2-D DIGE and LC-MS/MS. ⺠Constantly, 8 genes were downregulated and 9 genes were upregulated in pgl-1 mutants at both 20 °C and 25 °C. ⺠Among them, reduction of eef-1G was shown to be critical for the sterility of pgl-1 mutants. ⺠It was indicated that PGL-1 is involved in translational processes during the C. elegans germline development.
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Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Yukako Tohsato, Kanami Monobe, Kenji Suzuki, Toshiya Hayano, Ichiro Kawasaki, Masahiro Ito,