| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10556493 | Journal of Proteomics | 2012 | 11 Pages |
Abstract
⺠We identify that TDP is an anti-cancer drug candidate for HCC. ⺠We demonstrate that Hsp27 is one molecular target of TDP. ⺠Increasing Hsp27 expression will rescue TDP-induced apoptosis. ⺠TDP induced apoptosis through a caspase-dependent mitochondrial pathway.
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Physical Sciences and Engineering
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Analytical Chemistry
![Heat shock protein 27 mediates the effect of 1,3,5-trihydroxy-13,13-dimethyl-2H-pyran [7,6-b] xanthone on mitochondrial apoptosis in hepatocellular carcinoma](/preview/png/10556493.png "First Page Preview: Heat shock protein 27 mediates the effect of 1,3,5-trihydroxy-13,13-dimethyl-2H-pyran [7,6-b] xanthone on mitochondrial apoptosis in hepatocellular carcinoma")
Authors
Wei-ming Fu, Jin-fang Zhang, Hua Wang, Zhi-chao Xi, Wei-mao Wang, Peng Zhuang, Xiao Zhu, Shih-chi Chen, Tak-ming Chan, Kwong-Sak Leung, Gang Lu, Hong-Xi Xu, Hsiang-fu Kung,