| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10556850 | Microchemical Journal | 2011 | 15 Pages |
Abstract
Identified transformation products of atenolol are including its mono-, di and tri-hydroxylated derivatives as well as the aliphatic and aromatic ring breakdown products. Transformation of atenolol in the ozonation involved hydroxylation reaction, aromatic ring opening reaction, oxidation and cleavage of 2-hydroxy-3-(isopropylamino)propoxy group of atenolol. In ozonation, aromatic ring of atenolol was transformed through the reaction with both ozone and
- OH whereas the aliphatic chain of atenolol was degraded mainly through the reaction with
- OH. The results also indicated that both
- OH and ozone involved in the aromatic ring opening reaction.
- OH whereas the aliphatic chain of atenolol was degraded mainly through the reaction with
- OH. The results also indicated that both
- OH and ozone involved in the aromatic ring opening reaction.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Kheng Soo Tay, Noorsaadah Abd. Rahman, Mhd. Radzi Bin Abas,