Article ID Journal Published Year Pages File Type
10558318 Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2005 10 Pages PDF
Abstract
A key process in the development of new drugs is elucidation of the interaction between the drug molecule and the target protein. Such knowledge then makes it possible to make systematic structural modifications of the drug molecule to optimize the interaction. Many analytical techniques can be applied to proteins in solution such as circular dichroism, ultraviolet, and fluorescence spectroscopy but these all have limitations. In this paper, we investigate the feasibility of using relatively simple, visible light Raman spectroscopic methods to investigate amino acids and related biopolymers.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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