Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10559617 | Talanta | 2009 | 5 Pages |
Abstract
A simple and sensitive liquid chromatographic method coupled with electrogenerated chemiluminescence (ECL) was described for the separation and quantification of naproxen in human urine. The method was based on the ECL of naproxen in basic NaNO3 solution with a dual-electrode system. Factors affected the ECL emission were investigated. Under the optimal conditions, the ECL intensity has a linear relationship with the concentration of naproxen in the range of 4.0 Ã 10â8 g mLâ1 to 2.0 Ã 10â6 g mLâ1 and the detection limit was 1.6 Ã 10â8 g mLâ1 (S/N = 3). Application of the method to the analyses of naproxen in human urine proved feasible.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Yonghua Sun, Zhujun Zhang, Zhijun Xi, Zuolong Shi,