Article ID Journal Published Year Pages File Type
10559617 Talanta 2009 5 Pages PDF
Abstract
A simple and sensitive liquid chromatographic method coupled with electrogenerated chemiluminescence (ECL) was described for the separation and quantification of naproxen in human urine. The method was based on the ECL of naproxen in basic NaNO3 solution with a dual-electrode system. Factors affected the ECL emission were investigated. Under the optimal conditions, the ECL intensity has a linear relationship with the concentration of naproxen in the range of 4.0 × 10−8 g mL−1 to 2.0 × 10−6 g mL−1 and the detection limit was 1.6 × 10−8 g mL−1 (S/N = 3). Application of the method to the analyses of naproxen in human urine proved feasible.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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