Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10559779 | Talanta | 2011 | 8 Pages |
Abstract
In the present work, a new para-tert-butylcalix[4]arene-1,2-crown-4 bonded silica stationary phase (CBS4-4) was synthesized, structurally characterized, and employed to separate polycyclic aromatic hydrocarbons (PAHs), phenols, aromatic amines, benzoic acid and its derivatives. The chromatographic behaviors of the prepared stationary phase were investigated and compared with ODS. The effects of methanol concentrations on the retention index show that CBS4-4 exhibits high selectivity for the above analytes. The separation mechanisms based on the different interactions between calixarene and the analytes were discussed. With the assistance of quantum chemistry calculation, the interaction Gibbs free energy change ÎGsolv (in the mobile phase) of p, m and o-phenylenediamine positional isomers and para-tert-butylcalix[4]arene-1,2-crown-4 were obtained. The ÎGsolv values were consistent with the retention behavior of p, m and o-phenylenediamine on the CBS4-4. According to the chromatographic data, it can be concluded that the selectivity of CBS4-4 for analytes is mainly ascribed to hydrophobic interaction, accompanied by other effects such as hydrogen bonding interaction, Ï-Ï and inclusion interaction. The CBS4-4 column has been successfully employed for the analysis of benzoic acid in Sprite drink.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Kai Hu, Wenjie Zhao, Fuyong Wen, Junwei Liu, Xiaolan Zhao, Zhanhui Xu, Bailin Niu, Baoxian Ye, Yangjie Wu, Shusheng Zhang,