Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10560088 | Talanta | 2005 | 6 Pages |
Abstract
Epinephrine was found to be able to strongly enhance the electrochemiluminescence (ECL) of lucigenin system by using the anodic potential sweep. Based on which, a novel ECL method for the determination of epinephrine was developed. Under the optimum condition, the enhanced ECL intensity was linear with the epinephrine concentration in the range of 4.0 à 10â8 to 2.0 à 10â7 mol Lâ1. The detection limit (defined as S/N = 3) was 2.4 à 10â8 mol Lâ1, and the relative standard deviation was 2.7% for 1.0 à 10â7 mol Lâ1 epinephrine (n = 11). The method was successfully applied to the determination of epinephrine in pharmaceutical samples with satisfactory results. In addition, the possible mechanism for the lucigenin ECL system in the presence of epinephrine has also been discussed.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Yingying Su, Jian Wang, Guonan Chen,