Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10560112 | Talanta | 2011 | 9 Pages |
Abstract
A sensitive and selective electrochemical sensor based on a polyaniline modified carbon electrode for the determination of l-phenylalanine has been proposed by utilizing β-cyclodextrin (β-CD) incorporated multi-walled carbon nanotube (MWNT) and imprinted sol-gel film. The electrochemical behavior of the sensor towards l-phenylalanine was investigated by cyclic voltammetry (CV), differential pulse voltammetry (DPV), and amperometric i-t curve. The surface morphologies of layer-by-layer assembly electrodes were displayed by scanning electron microscope (SEM). The response mechanism of the imprinted sensor for l-phenylalanine was based on the inclusion interaction of β-CD and molecular recognition capacity of the imprinted film for l-phenylalanine. A linear calibration plot was obtained covering the concentration range from 5.0 Ã 10â7 to 1.0 Ã 10â4 mol Lâ1 with a detection limit of 1.0 Ã 10â9 mol Lâ1. With excellent sensitivity, selectivity, stability, reproducibility and recovery, the electrochemical imprinted sensor was used to detect l-phenylalanine in blood plasma samples successfully.
Related Topics
Physical Sciences and Engineering
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Authors
Yu-fang Hu, Zhao-hui Zhang, Hua-bin Zhang, Li-juan Luo, Shou-zhuo Yao,