Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10560547 | Talanta | 2011 | 7 Pages |
Abstract
A novel Cu2+-specific “off-on” fluorescent chemosensor of naphthalimide modified rhodamine B (naphthalimide modified rhodamine B chemosensor, NRC) was designed and synthesized, based on the equilibrium between the spirolactam (non-fluorescence) and the ring-opened amide (fluorescence). The chemosensor NRC showed high Cu2+-selective fluorescence enhancement over commonly coexistent metal ions or anions in neutral aqueous media. The limit of detection (LOD) based on 3 Ã δblank/k was obtained as low as 0.18 μM of Cu2+, as well as an excellent linearity of 0.05-4.5 μM (R = 0.999), indicating the chemosensor of high sensitivity and wide quantitation range. And also the coordination mode with 1:1 stoichiometry was proposed between NRC and Cu2+. In addition, the effects of pH, co-existing metal ions and anions, and the reversibility were investigated in detail. It was also demonstrated that the NRC could be used as an excellent “off-on” fluorescent chemosensor for the measurement of Cu2+ in living cells with satisfying results, which further displayed its valuable applications in biological systems.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Chunwei Yu, Lingxin Chen, Jun Zhang, Jinhua Li, Ping Liu, Wenhai Wang, Bing Yan,