Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10560893 | Talanta | 2005 | 5 Pages |
Abstract
Application of an integrated optics (IO) microcavity (MC) for evanescent excitation of two-photon excited fluorescence (TPF) is demonstrated. The MC provides a high local intensity, which is required for the TPF, because of resonant enhancement of the intracavity power and a strong two-dimensional confinement of the guided mode. Numerical estimations show a large increase, by more than a factor of 104 of the TPF intensity at the MC compared to a conventional straight waveguide. This will lead to a significant improvement of the detection limits of UV-absorbing chromophores (down to 10â8Â M) when using the MC as a biosensor. Feasibility of TPF excitation using an IO MC is confirmed experimentally for the first time.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Evgueni Krioukov, Dion Klunder, Alfred Driessen, Jan Greve, Cees Otto,