Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10560977 | Talanta | 2005 | 5 Pages |
Abstract
Linear calibration plots were obtained for naproxen concentrations up to 1 Ã 10â5 mol lâ1. The developed methodology exhibited a good precision, with a R.S.D. < 2.1% (n = 15). The detection limit of the determination was 1.9 Ã 10â7 mol lâ1 with a sampling rate of about 70 hâ1. The automatic method was applied to the determination of naproxen in pharmaceutical formulations. The obtained results were compared with those furnished by the reference procedure and the relative deviations were lower than 3.6%. No interference was found from the excipients usually used in solid pharmaceutical formulations.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Eftychia-Pavlina Zisiou, Paula C.A.G. Pinto, M. Lúcia M.F.S. Saraiva, Christophe Siquet, José L.F.C. Lima,