Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10561472 | Talanta | 2005 | 15 Pages |
Abstract
Different techniques and methods of electrochromatography on “lab on a chip” devices are reviewed. Described approaches include open-channel microchip electrochromatography relying on C8, C18 and novel gold nanoparticle (GNP) coating of microchannel wall; packed-channel microchip electrochromatography with new ways of automated loading and unloading of conventional octadecylsilica beads; monolith-based microchip electrochromatography with tailored casting of stationary phase at the specific places of microfluidic network and novel photolitographically fabricated collocated monolithic structures. Specific issues related to the microchip electrochromatography, i.e. importance of high aspect ratio of the microchannels in the open-channel electrochromatography or approaches eliminating the wall effect in the monolith-based electrochromatography, are discussed. Various applications for environmental, pharmacological, genomic and proteomic analysis are described. The operation parameters of reviewed microsystems are summarized in easy-to-read tables.
Keywords
EOF3-methacryloxypropyltrimethoxysilaneOctadecylsilica2-Acrylamido-2-methylpropanesulfonic acidMPTMSVSAPDADMACGNPAIBNTRISAMPsSSAODSSDSPDMSPAH2-(N-morpholino)-ethanesulfonic acidDNAStearyl methacrylateElectrochromatographyAcrylic acidPacking materialElectroosmotic flowBODIPYtwo-dimensionalsodium dodecyl sulfateMass spectrometryReverse phaseReviewMeSMonolithMiniaturizationMicrochipGold nanoparticleAspect ratioPolycyclic aromatic hydrocarbonPSGpoly(diallyldimethylammonium chloride)poly(dimethylsiloxane)Poly(methyl methacrylate)PMMACoatingPeptides
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Martin Pumera,