Article ID Journal Published Year Pages File Type
10561496 Talanta 2005 7 Pages PDF
Abstract
This paper describes glucose nanosensors based on the co-electrodeposition of a poly(vinylimidazole) complex of [Os(bpy)2Cl]+/2+ and glucose oxidase (GOD) on a low-noise carbon fiber nanoelectrodes (CFNE). The SEM image shows that the osmium redox polymer/enzyme composite film is uniform. The film modified CFNE exhibits the classical features of a kinetically fast redox couple bound to the electrode surface. A strong and stable electrocatalytic current is observed in the presence of glucose. Under the optimal experimental conditions, the nanosensor offers a highly sensitive and rapid response to glucose at an operating potential of 0.22 V. A wide linear dynamic rang of 0.01-15 mM range was achieved with a detection limit of 0.004 mM. Compared with the conventional gold electrode, the nanosensor possessed higher sensitivity and longer stability. Successful attempts were made in real time monitoring rabbit blood glucose levels.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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