Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10563899 | TrAC Trends in Analytical Chemistry | 2011 | 12 Pages |
Abstract
FFF can be coupled to different types of detectors that offer additional information and specificity, and the determination of size-dependent properties typically inaccessible to other techniques. The separation conditions need to be carefully adapted to account for specific particle properties, so quantitative analysis of heterogeneous or complex samples is difficult as soon as matrix constituents in the samples require contradictory separation conditions. The potential of FFF analysis should always be evaluated bearing in mind the impact of the necessary sample preparation, the information that can be retrieved from the chosen detection systems and the influence of the chosen separation conditions on all types of NP in the sample. A holistic methodological approach is preferable to a technique-focused one.
Keywords
SECFFFMALLSAF4UV-VisICP-OESDLSSize-exclusion chromatographyTemParticle-size analysisCharacterizationfield-flow fractionationMethod developmentParticle separationAnalytical separationInductively coupled plasma-optical emission spectrometryinductively coupled plasma-mass spectrometryMass spectrometryultraviolet-visible spectroscopyICP-MSSEMElectron microscopyScanning electron microscopyTransmission electron microscopyNanoparticleFood sampleEnvironmental sampleComplex sampleLight scatteringDynamic Light Scatteringliquid chromatographyhigh-performance liquid chromatographyHPLC
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Frank von der Kammer, Samuel Legros, Thilo Hofmann, Erik H. Larsen, Katrin Loeschner,