Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10564858 | Current Opinion in Chemical Biology | 2013 | 6 Pages |
Abstract
- We review advances of new oligomeric protein assemblies prepared by different strategies.
- Strategies - linkage of oligomerization domains with rigid linker, engineering of new interaction interfaces and covalent linkage of oligomerizing peptides - are described.
- The most recent strategy - topological fold prepared by using coiled-coil modules - is highlighted.
- The order of coiled-coil forming segments within a single chain can define the self-assembled structure.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Sabina BožiÄ, Tibor Doles, Helena GradiÅ¡ar, Roman Jerala,