| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10564860 | Current Opinion in Chemical Biology | 2013 | 8 Pages |
Abstract
- PPIs that are dominated by a continuous epitope are amenable for inhibition.
- A significant share of PPIs contains such 'hot segments'.
- Peptide-based inhibitors are obvious candidates for targeting these PPIs.
- Their poor bioavailability can be overcome via a plethora of optimization technologies.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Nir London, Barak Raveh, Ora Schueler-Furman,