| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10564869 | Current Opinion in Chemical Biology | 2013 | 7 Pages |
Abstract
- Heparin and heparan sulfate bind many proteins important to physiology and disease.
- Well-defined oligosaccharides can be accessed by chemical or chemoenzymatic means.
- Chemical synthesis advanced to deliver compounds of various lengths and complexity.
- Chain elongation by bacterial enzymes enhanced control in chemoenzymatic approach.
- Bioassay of the synthetic sugars gave insights to features required for function.
Related Topics
Physical Sciences and Engineering
Chemistry
Chemistry (General)
Authors
Medel Manuel L Zulueta, Shu-Yi Lin, Yu-Peng Hu, Shang-Cheng Hung,